Endocrine Abstracts

Introduction: The goiter represents the most common of all the disorders of the thyroid gland. Many Factors may be involved in the evolution of multinodular goiter. Although thyroid stimulating hormone (TSH) was described as the most important goitrogen factor, impairment of TRH-induced TSH release was reported with nodular goiter, suggesting thyroid autonomy. Herein, we report two cases of an isolated thyrotropin deficiency in patient presented with a voluminous goiter.<p...

Abnormal movements like hemichorea are rarely described as neurological manifestations of hyperglycemia. It is occur in nonketotic hyperglycemia with a pathognomonic radiological findings. We report a case of a 70 years old women with no past medical history who presented to the emergency department with abnormal limb movements. It was repetitive, brief, involuntary movement of the right arm evolving for 5 days. On admission, neurological examination showed right hemichorea. S...

Introduction: Hypothyroidism is not a common cause of renal failure which remains under-appreciated. Herein we report a case of acute renal failure in a patient with a severe primary hypothyroidism in whom hormone replacement therapy with Levothyroxine has significantly improved renal function.Observation: A 72-year-old man was referred to our department for primary hypothyroidism. His past medical history included a coronary heart disease with a heart f...

Introduction: Although Graves’ disease is often accompanied by other autoimmune diseases, only a few cases of Graves’ disease accompanied by pheochromocytoma have been described.Herein we report a rare case of coexisting Graves’ disease and pheochromocytoma.Observation: A 50-year-old male patient was referred to our department for the evaluation of right adrenal incidentaloma of 80*66 mm. He had a history of coronary...

Introduction: Widespread use of abdominal imaging has led to the identification of an increasing number of adrenal incidentalomas (AI) in the last decades. Causes of these adrenal masses are multiple.Aim: The aim of this study was to investigate the clinical and hormonal characteristics of AI.Materials and methods: The study was a retrospective monocentric analysis of 44 patients with AI who underwent radiographic and endocrine eva...

The risk of hypotension during Ramadan fasting in patients with adrenal insufficiency is unknown. The aim of our study was to evaluate objectively this risk.Methods: It is a prospective case-crossover study on 28 patients with known and treated AI. Patients had no hypertension and were regular fasters. All patients underwent a clinical examination and a 24-hours blood pressure monitoring during Ramadan fasting then outside fasting....

Introduction: Fahr syndrome is a rare entity characterized by the presence of bilateral intracranial calcifications with predilection for the basal ganglia and dentate nuclei. It is commonly associated with endocrine disorders, particularly parathyroid and Vitamin D disturbances. Herein we report a case of pseudohypoparathyroidism revealed by Fahr syndrome.Observation: A 29-old-year male was referred to our department for symptomatic hypocalcemia. He sho...

Introduction: Diabetic foot disease is a major health problem. The identification of its risk factors should guide preventive measures. The aim of this study was to determine the factors associated with diabetic foot complications.Patients and methods: It is a retrospective study including 47 patients admitted at the department of Endocrinology in La Rabta hospital for diabetic foot complications during the years 2015 and 2016. Clinical and para-clinical...

Introduction: Although the association between parathyroid and thyroid diseases is not uncommon, the coexisting of parathyroid adenoma causing primary hyperparathyroidism (PHPT) and papillary thyroid carcinoma (PTC) is rare. Probably this can be partially explained by different embryologic origin of thyroid and parathyroid cells. Herein, we report a case of PHPT associated with synchronous bifocal PTC.Observation: A 65-year-old woman was referred to our ...

Introduction: The involvement of the thyroid gland by tuberculosis is extremely uncommon even in countries in which tuberculosis is endemic. In the majority of the reported cases, thyroid function was preserved. Herein we report a case of thyroid tuberculosis in a patient with a primary hypothyroidism.Case report: A 52-year-old woman was referred to our department for a gradually growing goiter without compressive symptoms. She presented with a productiv...